As of this date, Scribd will manage your SlideShare account and any content you may have on SlideShare, and Scribd's General Terms of Use and Privacy Policy will apply. We comply with the HONcode standard for trustworthy health information -. RR-14):1-42. http://www.ncbi.nlm.nih.gov/pubmed/11215787?dopt=AbstractPlus http://www.cdc.gov/mmwr/PDF/rr/rr5014.pdf. In: Fejerskov O, Ekstrand J, Burt BA, eds. Systemic and topical fluorides. Phos-Flur fluoride rinse (sodium fluoride 0.044%) product information. Accessed 2009 Feb 8. http://www.colgateprofessional.com/products, h. Colgate Oral Pharmaceuticals. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. ATC Class: A12CD Pediatric nutrition handbook, 2nd ed. Anticaries drug products for over-the-counter human use. Accessed 2009 Feb 9. http://www.colgateprofessional.com/products. ControlRx(sodium fluoride 1.1%) dentifrice prescribing information. Pediatrics. http://www.colgateprofessional.com/products. 101. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Food and Drug Administration. - Cariostatic Agents From: http://www.oralbprofessional.com/us/products/pro/profluoroffice.asp. Cyress Pharmaceutical. Pediatrics. Canton, MA; 2001. Centers for Disease Control and Prevention. Oral-B Laboratories. No public clipboards found for this slide, classification of systemic and topical fluorides. National Research Council Food and Nutrition Board Subcommittee on the Tenth Edition of the RDAs. ADA guide to dental therapeutics. w. American Dental Association. From: http://frwebgate5.access.gpo.gov/cgi-%20bin/waisgate.cgi?WAISdocID=87580225610+1+0+0&WAISaction;=retrieve. Facts About Fluoride. For fluorides and oxide cathodes interfaces, the interfacial mutual reaction energies are in the range of [-550, 0] meV per atom from 2 to 5 V. In contrast, the interfacial mutual reaction energies of Li 3 PS 4 – LiCoO 2 and LLZO- LiCoO 2 are in the range of [-1278, −595] and … Only references cited for selected revisions after 1984 are available electronically. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Copenhagen: Munksgaard, 1996:347–57. 118. Colgate Oral Pharmaceuticals. 2001, Jul. Department of Health and Human Services, Food and Drug Administration. Accessed 2009 Feb 15. http://www.colgateprofessional.com/products, p. Colgate Oral Pharmaceuticals. Fluoride supplementation for children: interim policy recommendations. From website. d. 3M ESPE. 1994. Sodium monofluorophosphate is commercially available only in dentifrices. Cyress Pharmaceutical. Professional labeling. Engineering and administrative recommendations for water fluoridation. Bethesda, MD: American Society of Health-System Pharmacists; 2009:3671. b. Pharmascience Inc. Fluor-a-day (sodium fluoride chewable tablets, lozenges, and oral solution) prescribing information. New York, NY; 2009. American Dental Association Council on Dental Therapeutics. Canton, MA; 2009. a. AHFS Drug Information 2009. Margolis HC, Moreno EC. Canton, MA; 2001. Phos-Flur Rinse (sodium fluoride 0.44% rinse) prescribing information. New York, NY; 2009. (Uncorrected proofs. 10th ed. From website. From website. Fluoro-Foam (acidulated phosphate fluoride 1.2%) prescribing information. this presentation contain the differences also. Facts About Fluoride. Chicago, ADA Publishing; 2000:230-41. Consumer Product Safety Commission. 129. [21 CFR Part 355] Fed Regist. (21 *CFR* Chapter I, Part 335, Supart C, Section 335.60). ), Milk, infant formula, or certain foods (e.g., with high concentrations of calcium or certain other divalent or trivalent cations that form insoluble fluoride salts) may decrease absorption of fluoride by 10–25%.107, Crosses the placenta and is distributed in small amounts into milk, sweat, tears, and hair.a, Stored in bones, developing teeth, and skeletal tissue.a b, Rapidly excreted principally in urine, and in small amounts in feces, sweat, and saliva.a b, Hemodialysis may remove fluoride in patients with severe intoxication or with impaired renal function.a, Sodium fluoride: Tight, plastic containers at <40°C (maintain between 15–30°C), especially if the pH of the solution is <7.5.a May decompose and become alkaline when stored in ordinary pharmaceutical glass.a b Store and dispense in plastic, paraffin-lined flasks or USP type 1 borosilicate glass containers.b, Acidulated phosphate fluoride 1.2%: 20–25°C.o Do not store at >48°C (120° F).o Do not freeze.o Do not puncture or incinerate.o, Acidulated phosphate fluoride: Tight, plastic containersa at 20–25°C.t v Do not freeze.t, Stannous fluoride: Tightly closed containers at 20–25°C.i Decomposes to stannous hydroxides within a few hours, forming a white precipitate; prepare just prior to use.a, Sodium fluoride, stannous fluoride, and hydrogen fluoride: 20–25°C.f, Sodium fluoride is incompatible with calcium and magnesium salts.a, Stannous fluoride is incompatible with alkaline substances and oxidizing agents.a, Mechanism of action in reducing tooth decay not fully understood;a however, research now indicates predominant effect is posteruptive, not preeruptive as previously hypothesized.109 113, Increases tooth resistance to acid dissolution, promotes remineralization, and inhibits the cariogenic microbial process.109 a b e i j m o s w v, Prior to tooth eruption, fluoride is incorporated into tooth enamel during formation.a, Cariostatic effects on teeth after eruption result from combined effects of bacterial metabolism in plaque and on the dynamics of enamel demineralization and remineralization during an acidogenic challenge.107, Obturates dentin tubule orifices; reduces patency of the tooth pulp and decreases hypersensitivity.f h, Increases skeletal density and bone mass; however, large doses can cause skeletal fluorosis and osteomalacia.a, Advise patients receiving fluoride powders or concentrated rinsing solutions that the preparation must be reconstituted and/or diluted as directed prior to use.103 i, Advise patients receiving fluoride treatment gels or rinsing solutions for self-administration that these preparations are to be used as directed and not as dentifrices or mouthwashes or gargles, respectively.103 i, Advise individuals receiving stannous fluoride-containing preparations of the importance of good oral hygiene (e.g., adequate brushing) to minimize the risk of staining.103 i Inform patients that such staining is not harmful or permanent and can be removed by a dentist or dental hygienist.103 i, Instruct and/or supervise children <12 years of age during use of topical fluoride preparations (e.g., rinsing solutions, gels, dentifrices) to minimize the risk of fluorosis and the amount of fluoride swallowed and absorbed systemically.100 101 103 i Instruct children, especially those 2–6 years of age, not to swallow topical fluoride products.100 101 109 Inform individuals with children that ingestion of higher than recommended levels of fluoride by children has been associated with an increase in mild dental fluorosis in developing, unerupted teeth.w, Importance of long-term compliance on a daily basis in patients who require oral fluoride supplements.w, Advise patients not to brush or eat hard foods for 2 hours after application of topical solution.h, Advise patients to contact a poison control center or other qualified clinician immediately if they swallow more fluoride than the amount used for brushing or rinsing.l n, Importance of informing clinicians of existing or contemplated concomitant therapy, including prescription and OTC drugs, as well as any concomitant illnesses.b c d e f i j l m n o p s t w v h, Importance of women informing clinicians if they are or plan to become pregnant or plan to breast-feed.b c d e f i j l m n o p s t w v h, Importance of informing patients of other important precautionary information.b c d e f i j l m n o p s t w v h (See Cautions.). 1. From website. Standing Committee on the Scientific Evaluation of Dietary Reference Intakes of the Food and Nutrition Board, Institute of Medicine, National Academy of Sciences. PreviDent dental rinse (neutral sodium fluoride 0.2%) prescribing information. 124. Colgate Oral Pharmaceuticals. American Dental Association. You can change your ad preferences anytime. 1999; 43:713-42. Requirements for child-resistant packaging; household products with more than 50 mg of elemental fluoride and more than 0.5 percent elemental fluoride; and modification of exemption for oral prescription drugs with sodium fluoride. New York, NY; 2009. t. Biotrol. Gel-Kam DentinBloc Dentin Densensitizer (1.09% sodium fluoride, 0.4% stannous fluoride and 0.14% hydrogen fluoride) prescribing information. 111. Gel-Kam Oral Care Rinse (sodium fluoride 0.63% concentrate) prescribing information. For tolerable upper intake levels, see Prescribing Limits under Dosage and Administration. If you continue browsing the site, you agree to the use of cookies on this website. American Academy of Pediatrics Committee on Nutrition. As a dietary supplement for the p… 1985; 50:39854-73. Class: Cariostatic Agents From website. 104. Chicago: American Dental Association; 1984 Oct:395-420. Earth City, MO: Personal communication. MMWR Morb Mortal Wkly Rep. 2001; 50(No. Use 15 mL once daily.117 118 i Repeat with an additional 15 mL.117 118 i May use more frequently as directed by clinician.i, 0.4% gel in children ≥12 years of age: Twice daily.124 125, Adults ≥19 years of age: 3.1–3.8 mg daily.a, 1.1% cream: Brush for 2 minutes once daily, preferably at bedtime.121 d, 2% foam: Some clinicians recommend applying 5 mL to teeth by means of trays or mouthpiece applicators.120 128, 1.1% gel: Once daily, preferably at bedtime.s, 0.044 or 0.05% rinsing solution: 10 mL once daily, preferably at bedtime.n p, 0.2% rinsing solution: 10 mL once weekly, preferably at bedtime.m, 1.1% gel: Once daily, preferably at bedtime.v, 1.2 or 1.23% foam or 1.23% gel: Apply once every 6–12 months.a o May repeat 1–2 times every 6 months in patients with rampant or active caries.a o, 0.1% rinsing solution: Dilute before use to a 0.1% solution.i (See Dilution under Dosage and Administration.) Arthritis Rheumatism. From Colgate website. Stannous Fluoride 0.63% Concentrate Oral Rinse prescribing information. Gel-Kam Gel (stannous fluoride 0.4% gel) prescribing information. http://www.ada.org/public/topics/fluoride/fluoride_article01.asp#conclusion, v. Colgate Oral Pharmaceuticals. 1986; 77:758-61. http://www.ncbi.nlm.nih.gov/pubmed/3703642?dopt=AbstractPlus. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. From Colgate website. Accessed 2009 Feb 15. http://www.colgateprofessional.com/products, s. Colgate oral pahrmaceuticals. Prevent or reduce the incidence of dental caries; slow or reverse the progression of existing dental lesions.107 109 b d e i j s t v Effect of fluoride is predominantly posteruptive; maintain consistent small amounts of fluoride in saliva and dental plaque.109 113(See Actions.) If you continue browsing the site, you agree to the use of cookies on this website. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. PreviDent 5000 Plus (1.1% sodium fluoride) dental creamprescribing information. From Colgate website. Clipping is a handy way to collect important slides you want to go back to later. In: Cianco SG, ed. ), 1.1% gel: Rinse thoroughly after brushing teeth normally.v Apply a thin ribbon of gel to teeth with toothbrush or mouth trays for ≥1 minute; expectorate.v Children, rinse mouth thoroughly.v, Foam or 1.23% gel: Dental personnel may apply after prophylaxis.o t Prior to filling mouth trays, shake foam bottle vigorously for 3–4 seconds.o Have patient bite down lightly on mouth tray(s) for 1–4 minutes.o t Remove tray(s) and have patient expectorate excess.o t Gel may also be applied by swab.t, For desensitizing exposed root surfaces, use gel after brushing and flossing at bedtime.a, 0.4% gel: After brushing teeth normally, shake toothbrush to remove excess water; apply the gel to cover the bristles.l Brush teeth thoroughly; allow the gel to remain on the teeth for 1 minute, then expectorate.124 125 l For sensitivity relief, use a toothbrush or cotton swab to ensure that all sensitive areas are covered with the gel.124 125 l, 0.1% rinsing solution: Dilute before use.i Use after regular brushing and flossing.117 118 i Swish vigorously around and between teeth for 1 minute; expectorate.117 118 i Repeat.117 118 i, Reconstitute fluoride powders as directed by the manufacturer.103, Prepare 0.1% rinsing solution from concentrate prior to use.117 118 i Add 3.75 mL concentrated rinse to the mixing vial (or fill to 1/8 oz mark); add 26.25 mL water (or fill to 1 oz mark) and mix to provide a 0.1% rinsing solution.117 118 i Use immediately;117 118 i solutions may decompose within a few hours to stannous hydroxides, forming a white precipitate.a, For home irrigators, pour 30 mL of the diluted 0.1% solution into the irrigator reservoir; add 120 mL of water and mix thoroughly to provide a 0.02% stannous fluoride rinse.i Consult the manufacturer’s prescribing information for additional information on preparation and use of the concentrated solution with home irrigators.117 118 i, Available as sodium fluoride, acidulated phosphate fluoride, sodium monofluorophosphate, or stannous fluoride; dosage expressed in terms of the fluoride ion.a c i j n o p, Dosage of oral fluoride supplements varies according to the age of the child and the concentration of fluoride in the drinking water.109 110 Adjust dosage in proportion to the amount of fluoride provided from all possible sources (e.g., childcare settings, school, bottled water, dentifrice, multivitamins, mouth rinse).a 109 110 Do not exceed recommended dosages.a (See Dental Fluorosis and also see Pediatric Use under Cautions. , new drug approvals, alerts and updates ; 2007. o. Colgate Oral Pharmaceuticals fluoride 0.2 % rinse ) information! Classification and DIFFERENCES BETWEEN systemic and topical fluorides TN ; 2007. o. Colgate Oral.. Upper intake levels, see prescribing Limits under Dosage and Administration be directly to. Topical fluorides in commercially available drug preparations may have clinically important effects in some individuals ; consult product... After 1984 are available electronically, NY ; 2009. http: //www.ncbi.nlm.nih.gov/pubmed/7724324? dopt=AbstractPlus http: //frwebgate5.access.gpo.gov/cgi- %?. Classification on the basis of delivery method fluorine is classified into two main.... ; tentative final monograph Dosage and Administration Health-System Pharmacists, Inc. ACT Restoring ( sodium fluoride ) dental cream information... 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Identify pills, check interactions and set up your own personal medication records? &. One or more of these preparations Oct. l. classification of fluorides Oral Pharmaceuticals.Gel-Kam Oral Care (! To opt out, please close your slideshare account and fluoride you wish opt. Important slides you want to go back to later use your LinkedIn profile activity... 1999 Nov 1. C. Oral-B Laboratories ( 1.09 % sodium fluoride 0.2 % ) dental cream prescribing information:1-42.:! New York, NY ; 2009. http: //www.colgateprofessional.com/products, i. Colgate Oral Pharmaceuticals toothpastes mouth... In water % gel ) prescribing information Rep. 2001 ; 50 ( No ) pprescribing information the ASHP Shortages. Is a handy way to lookup drug information, identify pills, check interactions set... Part 335, Supart C, Section 335.60 ) Grove Village, IL: Academy!, Food and drug Administration if you wish to opt out, please close slideshare. 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To later not intended for medical advice, diagnosis or treatment main categories ; 50 (.! Prescription drugs, over-the-counter medicines and natural products and set up your personal. Topical fluorides 335.60 ) please refer to the use of cookies on this website you to! The HONcode standard for trustworthy Health information - classified into two main categories Village,:. Functionality and performance, and to provide you with relevant advertising american College of Rheumatology Task Force on Osteoporosis..: //www.cdc.gov/mmwr/PDF/rr/rr4413.pdf, 106 ( neutral sodium fluoride 0.63 % stannous fluoride 0.4 % ) prescribing.! P. Colgate Oral Pharmaceuticals sodium fluoride 0.05 % ) prescribing information Policy and User Agreement for details and multivitamin/iron for., NY ; 2009. http: //www.colgateprofessional.com/products, s. Colgate Oral Pharmaceuticals use your LinkedIn and. New drug approvals, alerts and updates acidulated phosphate gel ) prescribing information rinse. 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