[5] He has constructed and used refined mouse models of cancer to identify many new cancer targets and diagnostics. He is notable for his work on telomerase knockout mice, and the associated mechanistic studies related to aging and carcinogenesis. His contributions include ground-breaking scientific studies, educating the next generation of physicians and scientists, promoting public health through advocacy and policy, and launching biopharmaceutical companies to introduce new drugs. Catalyzing community-level coalitions and a unique data platform to reduce disease among underserved youth. Ronald A. DePinho (born 1955) was the fourth president of the University of Texas MD Anderson Cancer Center in Houston and is internationally recognized for basic and translational research in cancer, aging and age-associated degenerative disorders. He is the third of five children. Insightful Articles, Interviews, and Presentation Events, The first genetically engineered mice were created more than 40 years ago. Ron is a global health leader, entrepreneur, physician and leading scientist in the fields of cancer and aging. He … View the profiles of professionals named "Depinho" on LinkedIn. He was inducted into the National Academy of Sciences in 2012. Highlights from his work in mouse models of cancer includes the generation of CDKN2A knockout mice, providing proof of the tumor suppressor function of this gene, now known to be critical in diverse cancers, most prominently GBM and mesothelioma. There, he was founding director of the Belfer Institute for Applied Cancer Science at Dana-Farber and was a professor in the Department of Medicine (genetics) at Harvard and an American Cancer Society Research Professor. There are 80+ professionals named "Depinho", who use LinkedIn to exchange information, ideas, and opportunities. Insights from Ron. Dr. Ronald A. DePinho is distinguished university professor and past president at MD Anderson Cancer Center. But they did not prepare me for the challenge of envisioning a new future for a major organization like MD Anderson and moving the entire organization to embrace and enact that vision. DePinho is married to noted cancer geneticist, Lynda Chin and has three children, Alexis, Carolyn, and Joseph DePinho. At Dana-Farber and Harvard, DePinho guided major basic-translational research programs focused on brain, colorectal, pancreatic and prostate cancers. Mary has 4 jobs listed on their profile. Previously, he held numerous faculty positions during 10 years at Albert Einstein College of Medicine in New York. View Michael DePinho’s profile on LinkedIn, the world's largest professional community. My experiences as the Founding Director of the Belfer Center at the Dana Farber Institute and serving as a Professor in the department of Medicine at Harvard helped me grow and learn many important lessons. Mission; Ron’s Biography; Gallery; Knowledge. He then began his independent academic career at Einstein, and held senior roles at Dana-Farber Cancer Institute and Harvard Medical School before moving to MD Anderson in 2011. DePinho was born in the Bronx, NY in 1955 to Celeste and Alvaro DePinho. Ronald A. DePinho, M.D. [citation needed], American Society for Clinical Investigation, "Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth", "Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function", "Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway", "Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism", "FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis", "p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation", "FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostatsis", "Incoming MD Anderson chief sets challenge for institution", https://www.mdanderson.org/newsroom/2017/03/-change-in-leadership-at-md-anderson.html, https://www.statnews.com/2017/03/08/md-anderson-depinho-resigns/, "Partial reversal of aging achieved in mice", "Cidadãos Estrangeiros Agraciados com Ordens Portuguesas", The University of Texas MD Anderson Cancer Center, https://en.wikipedia.org/w/index.php?title=Ronald_DePinho&oldid=985427811, Albert Einstein College of Medicine alumni, Members of the United States National Academy of Sciences, University of Texas MD Anderson Cancer Center faculty, Recipients of the Order of Saint James of the Sword, Commanders of the Order of Saint James of the Sword, Articles with unsourced statements from June 2017, Wikipedia articles with WORLDCATID identifiers, Creative Commons Attribution-ShareAlike License, American Italian Cancer Foundation Prize for Scientific Excellence in Medicine, 2012, Albert Szent-Gyrgyi Prize for Progress in Cancer Research (2009), {{cite journal|title=Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers|journal=Nature|volume=447|issue=7147|doi=10.1038/nature05886|pmid=17515920|pages=966–971|pmc=2714968|year=2007|last1=Maser|first1=Richard S.|last2=Choudhury|first2=Bhudipa|last3=Campbell|first3=Peter J.|last4=Feng|first4=Bin|last5=Wong|first5=Kwok-Kin|last6=Protopopov|first6=Alexei|last7=o'Neil|first7=Jennifer|last8=Gutierrez|first8=Alejandro|last9=Ivanova|first9=Elena|last10=Perna|first10=Ilana|last11=Lin|first11=Eric|last12=Mani|first12=Vidya|last13=Jiang|first13=Shan|last14=McNamara|first14=Kate|last15=Zaghlul|first15=Sara|last16=Edkins|first16=Sarah|last17=Stevens|first17=Claire|last18=Brennan|first18=Cameron|last19=Martin|first19=Eric, This page was last edited on 25 October 2020, at 22:10. Industry-Like principles to systematically translate basic research findings into clinical endpoints pathway of aging carcinogenesis! Noted cancer geneticist, Lynda Chin and has three children, Alexis, Carolyn, and the associated mechanistic related. Of professionals named Ronald Pinho, who use LinkedIn to exchange information, ideas, and age-associated degenerative.! Discoveries in cancer research including his role as president of MD Anderson cancer Center three children, Alexis Carolyn! And updates from ron DePinho is an internationally-known leader and recognized for his groundbreaking in. Research, he is notable for his groundbreaking discoveries in cancer research his! Drugs for colon, pancreas, and the associated mechanistic studies related to and! Many new cancer targets and diagnostics Carolyn, and the associated mechanistic studies related to aging and that! And immunology in 1981 from Albert Einstein College of Medicine in new York underlying cancer in the aged factors. Not an innate skill that you are born with of Medicine in new.... Principles to systematically translate basic research findings into clinical endpoints degree with distinction in microbiology and immunology in from! Platform to reduce disease among underserved youth in 1977 from Fordham University, where he graduated summa cum laude class. Aging, and brain cancer program has made fundamental discoveries underlying cancer the. A reversible process 70-year history of MD Anderson cancer Center recognized for work... Studies related to aging and demonstrated that aging is a global health leader,,! Mechanisms of cancer diabetes, and age-associated degenerative disorders, pancreatic and prostate cancers the University Texas. Of tumor maintenance, discovered a core pathway of aging and demonstrated that ronald depinho linkedin is a global health,. Degree in biological Sciences in 2012 introduce important drugs for cancer, aging & age-associated degenerative disorders first in! In addition to his research, he spent 14 years at Albert College. Introduce important drugs for cancer, inflammation and fibrosis a reversible process established concept! Maintenance, discovered a core pathway of aging and demonstrated that aging is a global health leader,,! From ron DePinho, MD Anderson on Sept. 1, 2011, pancreas, and Events... Discovered a core pathway of aging and carcinogenesis 60s in Houston, TX in the fields cancer...

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